Knowledge of HPV-Associated Head and Neck and Oral Cancers Among Health Care Students in Mexico

Background: The human papillomavirus (HPV) vaccine was first approved for use in females in 2006, and then in 2009, for both males and females. However, the knowledge of HPV and HPV vaccine, and uptake of the vaccine has been suboptimal and worse among males. In addition, the burden of HPV-associated cancers in the United States is very high among males, especially in head and neck, anal, and penile cancers. If the current HPV vaccination trend persists, then the Healthy People 2020 goal of achieving 80% HPV vaccination will not be achieved. Objective: The aim of this study was to quantify gaps in HPV and HPV vaccine knowledge among adult males in the United States. Methods: Data from the Health Information National Trends Survey 4 Cycle 4 (November 2014) were analyzed for 3,677 survey participants aged 18 years and older. Primary outcome of interest was men's knowledge of HPV and HPV vaccine. Secondary outcome of interest were men's knowledge that HPV causes certain cancers. Participants were asked if they have heard about the HPV and HPV vaccine. Respondents who answered “no” were excluded (n = 1,389). Final sample size used for analyses for the secondary outcomes of interest was 2,288. Results: Sixty-four percent of respondents (56% of men and 72% of women) had heard of HPV and the HPV vaccine. In multivariate analyses, after adjusting for known covariates, males were 67% (95% CI: 0.25 – 0.45) less likely to have heard of HPV, and 76% (95% CI: 0.18 – 0.32) less likely to have heard of the HPV vaccine compared to females. Seventy percent (73% of men and 67% of women) knew that HPV is sexually transmitted disease (STD), 78% (76% of men and 79% of women) knew HPV causes cervical cancer, but only 29% of men and women knew it causes penile cancer, 26% (27% of men and 25 % of women) knew it causes anal cancer, and 30% (31% of men and 29% of women) knew it causes oral cancer. Among those that had heard of HPV, there was no statistical difference in knowledge between males and females with regard to the knowledge that HPV causes cervical, penile, anal and oral cancer. However males were less likely than females to know that HPV causes cervical cancer while females were less likely to know that HPV causes oral cancer. Modified by race, non-Hispanic Black women were 54% less likely to have heard of HPV (OR = 0.46, 95% CI: 0.24 – 0.88); and 64% less likely to have heard of HPV vaccine (OR = 0.36, 95% CI: 0.19 – 0.67), compared to non-Hispanic White women. Similarly, compared to non-Hispanic White women, Hispanic women were 51% less likely to have heard of HPV vaccine (OR = 0.49, 95% CI: 0.27 – 0.88). For men, compared to non-Hispanic White men, Hispanic men were 69% less likely to have heard of HPV vaccine (OR = 0.31, 95% CI: 0.16 – 0.62). Conclusion: A two-third of respondents were aware of HPV and HPV vaccine, but a clear gender and racial gap still exist in HPV and HPV vaccine knowledge. This underscores the need for more tailored interventions specifically targeted towards males and minority racial groups in order to increase knowledge and uptake of the HPV vaccine. It also highlights the need for more deliberate efforts on the part of physicians to discuss the HPV vaccine with eligible patients and parents Citation Format: Nosayaba Osazuwa-Peters, Eric Adjei Boakye, Betelihem B. Tobo, Kahee Agid Mohammed. HPV is not just a woman's business! Understanding the gaps in men's knowledge of HPV and HPV vaccine. [abstract]. In: Proceedings of the Eighth AACR Conference on The Science of Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; Nov 13-16, 2015; Atlanta, GA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2016;25(3 Suppl):Abstract nr B89.

Background: Awareness and knowledge of human papillomavirus (HPV) and HPV vaccine are critical antecedents of HPV vaccine uptake. While emerging literature has examined racial and ethnic differences in these areas, most either exclude Asian Americans, subsume them under the category of “other,” or aggregate all origin groups under a single category of “Asians.” To fill this gap in the literature regarding data disaggregation, we conducted an analysis of awareness and knowledge of HPV, the HPV vaccine, and HPV-related cancers among six Asian origin groups (Chinese, Filipinos, Indians, Japanese, Koreans, and Vietnamese), using nationally representative samples. Methods: We performed a pooled cross-sectional study utilizing the Health Information National Trend Survey data (HINTS-4 cycle 4 [2014], HINTS-5 cycles 1-3 [2017-2019]), a nationally representative survey administered by the National Cancer Institute. We analyzed questions about knowledge of HPV, the HPV vaccine, and the facts that HPV causes cervical, oral, anal, and penile cancers by race and/or ethnicity. The sample included those who self-reported as Chinese, Filipino, Indian, Japanese, Korean, or Vietnamese origins; non-Hispanic White (NHW) respondents were the reference group. We used survey-design adjusted Wald chi-square tests. Results: A total of 8,865 non-Hispanic White respondents and 623 Asian respondents were included in this study. Significantly lower proportions of most Asian origin groups (Chinese 45.5%; Indian 45.6%; Korean 39.7%; and Vietnamese 43.5%) had heard of HPV compared with NHW counterparts (69.4%). Significantly lower proportions of Chinese (50.9%), Filipino (47.0%) Korean (46.1%), and Vietnamese (38.8%) respondents had heard of the HPV vaccine compared with NHW respondents (68.1%). Significantly lower proportions of Chinese (41.0%), Indian (36.2%), Korean (32.9%), and Vietnamese (30.6%) respondents knew that HPV causes cervical cancer compared with NHW (55.7%). Significantly lower proportions of Chinese and Vietnamese respondents knew that HPV causes anal and oral cancers, and significantly lower proportions of Indian respondents knew that HPV causes penile cancer, when compared to NHW counterparts. Discussion: Most Asian origin groups had lower knowledge of HPV-related facts, with varying magnitudes, compared with NHW counterparts. Vietnamese and Chinese respondents had significantly lower knowledge compared with NHW respondents for 5 out of 6 questions. For most questions, Vietnamese was the group with the lowest proportions of respondents reporting knowledge. Heterogeneity in HPV-related knowledge suggests the need to culturally tailor interventions about the HPV vaccine in appropriate languages to effectively reach different Asian origin groups, with particular attention to those with low awareness. Continued monitoring of HPV-related knowledge with disaggregated data collection for Asian origin groups is critical for efforts to increase educational outreach, combat vaccine misinformation, and improve HPV vaccine uptake. Citation Format: Milkie Vu, Yenan Zhu, Duy D. Trinh, Young-Rock Hong, Ryan Suk. A population-based analysis of awareness and knowledge of HPV and HPV vaccine among Asian American adults by origin group, 2014-2019 [abstract]. In: Proceedings of the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2023 Sep 29-Oct 2;Orlando, FL. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2023;32(12 Suppl):Abstract nr C140.

HPV vaccination rates remain low: cancer prevention community needs to continue promoting the vaccine's safety and efficacy, say experts.

Background: Human papillomavirus (HPV) is a causative agent in cervical cancer as well as anal, oropharyngeal, penile, and vaginal/vulvar cancers. Licensed, effective HPV vaccines have been available in the U.S. since mid-2006 for females and late 2011 for males and are recommended up to age 26. Despite this, in 2014, only 39.7% of U.S. girls and 21.6% of boys 13 to 17 years of age completed the three-dose vaccine series. ‘Lack of knowledge’ was a primary reason cited among parents for not vaccinating their children. HPV vaccination rates are lower still among 19-26 year olds, particularly among the uninsured. We assessed awareness and knowledge of HPV disease, HPV-related cancers, and HPV vaccines among working, uninsured adults and used 2014 data from the Health Information National Trends Survey (HINTS cycle 4) as a national benchmark against which to compare our data. Methods: Self-administered surveys were offered to patients attending appointments at the Volunteers in Medicine (VIM) clinic in Jacksonville, FL between September 10, 2014 and October 24, 2014. VIM provides free primary care for working individuals without insurance living and/or working in Duval County. Patients were eligible to participate if they were at least 18 years of age, not in acute distress, and had not completed a survey during pilot-testing. Surveys were available in English and Spanish and contained a validated HPV knowledge measure assessing disease knowledge and vaccine knowledge. Additionally, HPV-related cancer knowledge was assessed: 5 HPV-related (cervical, anal, throat, penile, vaginal/vulvar) and 4 not currently known to be HPV-related (lung, breast, prostate, skin). High knowledge was defined as having a knowledge score in the upper quartile of positive values. Odds ratios (OR) and 95% confidence intervals (CI) were estimated using logistic regression to assess the association of demographic characteristics with having high knowledge of HPV, HPV vaccines, and HPV-related cancer. Additional models assessed individual cancers. During the study period 356 patients were eligible to participate; of these, 55 declined (84% participation rate). Of the 301 surveys, 5 surveys were excluded from analysis due to excessive missing data; a total of 296 surveys were analyzed. Results: 50.3% of participants (n=149) had heard of HPV, 37.2% (n=110) correctly indicated that HPV is sexually transmitted, and 32.1% (n=95) had heard of the HPV vaccine. In HINTS 4, these estimates were 63.6%, 44.0%, and 62.7%, respectively. In adjusted models, high HPV disease knowledge was associated with race (OR non-white = 0.39 (0.19, 0.78)) and education (OR >high school = 2.34 (1.14, 4.84)) while high HPV vaccine knowledge was associated with race (OR non-white = 0.42 (0.21, 0.82)), education (OR >high school = 5.04 (2.30, 11.06)), and sex (OR male = 0.34 (0.12, 0.94)). Of the HPV-related cancers, 43.9% answered correctly for cervical, 9.1% for anal, 11.1% for mouth/throat, 11.5% for penile, and 30.7% for vaginal/vulvar cancer. Males were less likely than females to know that HPV is a causative agent for cervical (OR=0.41 (0.22, 0.75)) and vaginal/vulvar cancers (OR=0.43 (0.22, 0.86)). Conclusion: Using estimates obtained in HINTS 4 as a benchmark, awareness and knowledge of HPV, HPV-related cancers, and HPV vaccines were low among working, uninsured adult patients. In addition to improving access to HPV vaccination (e.g. volunteer clinics), the findings demonstrate a need for strategies to educate medically underserved adults about HPV. Maximizing access to HPV vaccination, including catch-up vaccination for adults up to age 26 are consistent with the recommendations of the President's Cancer Panel, the American College of Obstetricians and Gynecologists, the American College of Physicians, and the Advisory Committee on Immunization Practices. Citation Format: Carmen Radecki Breitkopf, Lila Finney Rutten, Debra Jacobson, Patrick Wilson, Monica Albertie, Robert M. Jacobson, Gerardo Colon-Otero. Awareness and knowledge of HPV, HPV-related cancers, and HPV vaccines in a working, uninsured clinic population. [abstract]. In: Proceedings of the Eighth AACR Conference on The Science of Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; Nov 13-16, 2015; Atlanta, GA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2016;25(3 Suppl):Abstract nr B91.

Human Papillomavirus and Vaccination

In spite of the volume of information of Human Papilloma Virus (HPV) and the HPV vaccines, there are racial and gender differences in the knowledge and awareness of HPV among Guyanese. The study aimed to assess the knowledge and attitude towards HPV infection, cervical cancer and HPV vaccines. The study was conducted among 198 students studying at University of Guyana. Semi-structured questionnaires were administered to evaluate students’ knowledge, attitude and information of HPV, HPV associated diseases and vaccines. In all, 36.4% males and 63.6% females participated in the study of which 38.9%, 45.9% and 15.2% were Afro-Guyanese, Indo-Guyanese other racial groups respectively. By gender, 18.2% had heard of HPV, 41.9% had little knowledge of HPV and 39.9% had no knowledge of HPV. Regarding knowledge on HPV vaccine and genital warts, 54.5 % of the participants neither agreed nor disagreed with the fact that, these vaccines can protect the individual from genital warts, 19.2% agreed but 26.2% disagreed. Racially, only 1.0% agreed that males spread HPV, 16.7% says females, 29.8% says both and 52.5% had no knowledge of the spread of HPV. Again, 59.6% of these racial groups had no knowledge of the link between HPV and cervical cancer, 31.8% true whereas 8.6% answered false. Among these participants who have heard about the HPV, 19.2% had the information from health education programs whereas 17.2% had it from friends/acquaintances. HPV infection is asymptomatic and both males and fe-males are at high risk of contracting HPV related diseases. Although some participants had heard of HPV, their knowledge was limited. Therefore, health-care providers in Guyana should focus on providing information and education to the populace rather than the diagnosis and treatment of HPV infections and its associate cancers. Keywords : Sexually transmitted virus, cancer-causing virus, incidence rate, students

There is a high burden of cervical cancer in the Caribbean region, particularly in the Bahamas, yet there are few studies of Human Papillomavirus (HPV) and HPV vaccine in the region. The objective of this study was to assess the knowledge and awareness of HPV and the HPV vaccine among school-aged youth (15–18 years) living in the Bahamas. Cross-sectional data were obtained from the “Getting to Zero” HIV study in the Bahamas conducted in 2014/2015 (n = 1553). The questionnaire elicited information on knowledge of HPV and HPV vaccines, using previously validated scales. Data analysis included Chi-square tests and Mann Whitney U test. In this sample of school-aged youth, only 10.7% (146/1364) had ever heard of HPV. With respect to those who were sexually active (n = 685), only 10.7% had ever heard of HPV. For those who had heard of HPV, knowledge of HPV and HPV vaccines was assessed on an HPV Knowledge and HPV Vaccine Knowledge scale, respectively. There was no statistically significant difference in mean HPV knowledge score between males and females, or HPV vaccine knowledge scores, between males and females. There was a general lack of awareness of HPV and HPV vaccines among school-aged youth in the Bahamas. This is an important gap in the HPV vaccine strategy and cancer prevention, as this is the age at which most people acquire HPV. It emphasizes the importance of developing a careful implementation plan, with an evaluation of knowledge and attitudes, in order to have an effective HPV vaccine uptake.

Introduction:Human papillomavirus (HPV) causes the most common sexually transmitted infection (STI) in the world. It affects people regardless of gender and age, causing genital warts and cancer. Objective:To evaluate university students’ knowledge of HPV and its relationship with head and neck and oral cancers. Methods: This is a cross-sectional study using an online questionnaire administered to undergraduate students at a public university (n=335). Results:In total, 69.3% of the participants were unaware of the relationship between HPV and head and neck cancers and 34.6% claimed that HPV may not cause oral cancer. The chances of knowing about the relationship of HPV with head and neck cancers were significant for participants who knew that HPV could be asymptomatic (OR = 9.9; p = 0.029), that might cause genital warts in men (OR = 4.0; p = 0.015), and those aged 24 years or older (OR = 1.9; p = 0.021). However, undergraduate students in the field of health and medicine (OR = 0.419; p = 0.002), who had sex at least twice a week (OR = 0.471; p = 0.017), and were unaware of the target public for the HPV vaccine (OR: 0.222, p<0.001) were less likely to know about the relationship. Students who knew of the relationship between HPV and female (OR = 3.6; p = 0.010) and male genital warts (OR = 3.0; p = 0.005) or were immunized (OR = 1.8; p = 0.020) were more likely to understand the viral interaction with oral cancer. Those who were unaware of the population eligible for HPV vaccine (OR = 0.493; p = 0.017) also showed gaps in their knowledge of this relationship. Conclusion: Our findings showed that there were limitations in the knowledge about HPV, its vaccine, and its relationship with head and neck and oral cancers.

Prior to its planned introduction, we investigated predictors of baseline knowledge and acceptability of HPV vaccination among medical and allied health care students in Kano, northern Nigeria. A total of 410 medical, dental and allied health students completed structured validated questionnaires. Knowledge scores and acceptability of HPV vaccine were determined and adjusted odds ratios (AOR) for predictors of HPV knowledge and acceptability were derived from multivariate logistic regression models. Overall, 3.7% (n = 15), 30.7% (n = 126) and 65.6% (n = 269) of respondents had good, moderate, and poor knowledge of HPV, respectively. The majority 334 (81.5%) were willing to accept the HPV vaccine, but only 18 (4.4%) had received at least one dose of the vaccine. Knowledge of HPV was better among females, younger (<20 years) medical students, students at higher levels of study, sexually experienced students, and condom users. HPV vaccine acceptance was higher among female students in the faculty of allied health with a family history of cervical cancer and good or moderate knowledge of HPV. In conclusion, most students were willing to receive HPV vaccination, despite their sub-optimal level of knowledge and low vaccine uptake. We recommend piloting the HPV vaccine in health colleges and recruiting early adopters as peer educators and advocates. IMPACT STATEMENT What is already known on this subject? Human Papilloma Virus (HPV) vaccine has been introduced in over 80 countries in the past decade, but evidence suggests low awareness of HPV infection and the vaccine, especially in developing countries. Nigeria proposes to introduce the HPV vaccine as part of the routine immunisation program in early 2021. What do the results of this study add? The majority of medical and allied health students in Kano, Nigeria, were willing to receive HPV vaccination, despite their sub-optimal level of knowledge and low vaccine uptake. Vaccine acceptance was predicted by the respondent’s sex, course of study, family history of cervical cancer and knowledge of HPV. What are the implications of these findings for clinical practice and/or further research? The findings could inform program implementation and evaluation as HPV vaccine uptake is scaled up across Africa.

Public health information and educational interventions regarding human papillomavirus (HPV) have focused on the link between vaginal sex and cervical cancer among women. Many people are unaware that HPV can be transmitted through oral sex or that HPV causes oral cancers. Given that HPV infections and unprotected oral sex are increasing, research on oral sex-related HPV risk is important. This study examined the effect of a brief informational intervention regarding HPV and oral sex on the sexual risk cognitions of young adults. College students (N = 238) read information on HPV, oral sex, and oral cancer or no information. Participants then completed measures of oral sex and HPV knowledge, oral sex willingness, HPV vaccination likelihood, and risk perceptions. Participants who read the information on HPV and oral sex and cancer (compared to those who did not) reported greater knowledge, perceived risk and concern, and lower willingness to engage in oral sex. These effects were only significant among women. However, men reported a higher likelihood of future HPV vaccination compared to women who had not yet received the vaccine. Focusing on oral sex and cancer, this study adds to research investigating ways to reduce HPV infections.

The aim of this study is to assess dental students’ opinions of the dentists’ role in primary prevention of human papillomavirus (HPV)-related oral cancer using a cross-sectional web-based survey. A questionnaire, containing questions about knowledge of HPV and oral cancer, confidence in head and neck examination and role of the dentist in preventing HPV-related oral cancer, was sent to all students of the Academic Centre of Dentistry Amsterdam (n = 912). One hundred and twenty-six (n = 126) students completed the questionnaire. Significantly, more master students (75%) than bachelor students (54.3%) were aware that HPV is a causative factor for oral cancer. Master students had more knowledge of HPV than bachelor students, but knowledge about HPV vaccination was irrespective of the study phase. The majority of dental students agreed that it is important to discuss HPV vaccination with patients. Eighty-nine percent of the students think that more education about symptoms of oral cancer will increase screening for oral cancer. Development of a protocol for screening in dental practices was considered even more important. According to dental students, dentists should discuss HPV as a risk factor for oral cancer with patients. Future dentists are willing to be involved in both primary and secondary prevention of HPV-related oral cancer. Therefore, screening for oral cancer and education about HPV vaccination should be integral elements of the dental curriculum.

This study was conducted to determine women's health beliefs about HPV and HPV vaccination and factors associated with health beliefs. This cross-sectional study was conducted with 300 women aged 21-64 in Turkey. Data were collected using the human papillomavirus (HPV) knowledge scale (HPV-KS) and the health belief model scale for human papillomavirus and its vaccination (HBMS-HPVV). The mean age of the women who participated in the study was 35.16±9.52 years. Of them, 72.3% heard of the HPV test, 30.3% had an HPV test, 62% heard of HPV vaccination, and 9.7% had HPV vaccination. Educational level, hearing about the HPV vaccine, and HPV knowledge level were significant predictors of perceived benefit (p<.001). HPV knowledge level significantly predicted perceived susceptibility (p<.001). HPV knowledge level and hearing about HPV tests and vaccines were significant predictors of perceived severity (p<.001). A high level of education, a high level of HPV knowledge, and hearing about HPV tests and the HPV vaccine positively affect women's health beliefs. Health belief model-based education programs should be used to improve women's HPV knowledge and health beliefs about HPV and the HPV vaccine. In addition to women's health beliefs, cervical cancers can only be prevented by including the HPV vaccine in national immunization programs and increasing the coverage of HPV screening tests.

Background: Human papillomavirus (HPV) is the most common sexually transmitted infection in the U.S. Cervical cancer (CC) is the most common HPV-associated cancer, and Korean Americans (KAs) experience one of the highest CC incidence and mortality rates among Asian Americans. Awareness and knowledge of HPV and HPV vaccine are essential in preventing HPV-associated cancers; however, studies emphasize low HPV awareness and knowledge among KAs. Although HPV causes cancers in both men and women, there exist misconceptions that the HPV vaccine is only for women and not for men. Furthermore, research on HPV vaccination among KAs has been conducted mostly among women. The health belief model (HBM) is a value-expectancy theory that is used to explain and predict individual changes in health behaviors and has been used in multiple studies that aimed to understand HPV vaccination behavior. Purpose: The purpose of this study is to develop an HBM guided text messaging program to increase HPV awareness, knowledge, and HPV vaccination among Korean young adults in the U.S. Methods: A total of 10 Korean young adults between the ages of 18 and 26 completed the mixed methods study. The survey examined HPV, HPV vaccine, and cervical cancer awareness and knowledge, beliefs, and vaccination intention. The qualitative interview with cognitive response testing (CRT) of the text messages, which were preconstructed based on previous literature and six constructs of HBM, allowed participants to provide feedback on the comprehension and emotional response to the messages, and any other recommendations to improve the content and delivery of the messages. Results: All participants (N=10) indicated to have never received the HPV vaccine and most participants had no intention to receive the HPV vaccine within one year. Although most of the participants were aware of HPV and HPV vaccine, overall knowledge of HPV, HPV vaccine, and cervical cancer were low. The interviews revealed that reasons for vaccine hesitancy and non-vaccination included cost, inconvenience, and low perceived susceptibility. Especially, there was low perception of the importance of HPV vaccination for males. Overall, findings from the CRT showed that there was a clear understanding of the preconstructed text messages. There was a consensus on the duration and timing of the messages and participants provided recommendations on the content, tone, and structure of the messages. Using the HBM, participants’ feedback on HPV awareness, knowledge, and vaccination intention, the text messaging library was revised and includes a total of 9 text messages over the four days. Conclusions: This study provides important insights into the development of an educational text messaging program among Korean young adults in the U.S. Current study will build a foundation for an educational mobile health program to help increase awareness and knowledge of HPV and HPV-associated cancers, as well as HPV vaccination intention, and impact HPV-associated cancer rates among KAs through vaccination in the long term. Citation Format: Min Jeong Jeon, Daisy Le. Development of an educational text messaging program to improve human papillomavirus awareness, knowledge, and vaccination intention among Korean young adults in the U.S. [abstract]. In: Proceedings of the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2023 Sep 29-Oct 2;Orlando, FL. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2023;32(12 Suppl):Abstract nr C101.

Increasing HPV vaccine interest via standardized multimodal education in an underserved patient population (363)

Introduction: Racial/ethnic (R/E) minorities have been shown to have lower knowledge of Human Papillomavirus (HPV) and the HPV vaccine when compared to R/E majorities. They are also less likely to have a regular healthcare provider (HCP). Given that having a regular HCP is associated with higher knowledge of HPV, the HPV vaccine, and higher vaccine completion rates, we sought to evaluate whether R/E disparities in HPV knowledge are attenuated among individuals with a regular HCP. Methods: Weighted data from the Health Information National Trends Survey (HINTS) 5 cycle 1 and 2 (2017-2018) were analyzed using SAS Version 9.4. Self-reported race/ethnicity was used to categorize participants as R/E minority (Black/African American, Hispanic, and Other) or majority (White). Wald chi-square tests were performed to assess the association between R/E minority status and knowledge of HPV and the HPV vaccine. Multivariate logistic regression was used to assess these associations after controlling for pertinent sociodemographic factors (gender, age, education, income, health insurance, geographic area, census region, ever having cancer, and use of the internet). The same associations were assessed in stratified analyses comparing those with and without a regular HCP. Results: Overall, knowledge of HPV and the HPV vaccine was significantly lower among minorities than among majorities (57.62% and 52.51% vs 65.39% and 66.38%). A lower percentage of minorities reported having a regular HCP (52.20%) when compared to majorities (72.71%). While knowledge of HPV and the HPV vaccine was generally higher among individuals with a regular HCP (62.94% compared to 57.84% among those without a regular HCP), differences by R/E status persisted. Specifically, a lower proportion of minorities with a regular HCP had ever heard of HPV (61.40%) or the HPV vaccine (55.14%), when compared to majorities (67% and 67.89%, respectively). In multivariate analyses, minorities had a 35% lower odds of having heard of HPV (odds ratio [OR] = 0.65, confidence interval [CI] = 0.50 – 0.84) and a 45% lower odds of having heard of the HPV vaccine (OR = 0.55, CI = 0.42 – 0.73) when compared to majorities after adjusting for sociodemographic factors. Furthermore, among individuals with a regular HCP, minorities had a 37% (OR = 0.63, CI = 0.48 – 0.83) lower odds of having heard of HPV and a 49% (OR = 0.51, CI = 0.39 – 0.68) lower odds of having heard of the HPV vaccine when compared to majorities after adjusting for sociodemographic factors. Conclusion: These analyses show that R/E minority groups have disparately lower knowledge of HPV and the HPV vaccine when compared to the R/E majority group. Additionally, minorities who had a regular HCP still reported significantly lower levels of HPV and HPV vaccine knowledge than their majority counterparts. These analyses suggest the need to address disparities in health information and strengthen provider-patient communication regarding HPV and the HPV vaccine. Citation Format: Jane Montealegre. Racial/ethnic disparities in knowledge of human papilloma virus (HPV) and the HPV vaccine among individuals with a regular healthcare provider: Results from the Health Information National Trends Survey, United States, 2017-2018 [abstract]. In: Proceedings of the Twelfth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2019 Sep 20-23; San Francisco, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2020;29(6 Suppl_2):Abstract nr D009.