Abstract
Neurofilament light chain (NFL) has been proposed as a reliable and validated prognostic biomarker for amyotrophic lateral sclerosis (ALS). Usually, fast and slow progressors (FP and SP respectively) of disease were identified according to the slopes of the revised ALS functional rating scale. We aim to evaluate the prognostic value of King's stage progression rate (KPR) through cerebrospinal fluid (CSF) neurofilament light chain (NFL) assessment.
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