Abstract
The theory of crystallization of binary chains ( Chernov, 1965) has been used to study the kinetics of replication of copolymeric DNA. The importance of the stacking and bond energies in the process of replication is emphasized. The dependence of rate of replication on the distribution of base pairs for the same ratio of ( G + C) and ( A + T) bases in DNA is established. Analytic formulae are given for the rate of replication for copolymeric DNA with regular and random distribution of base pairs in terms of frequencies of the addition and dissolution of hydrogen bonds. A comparison is made with the observed rates of replications for synthetic and natural DNA.
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