Abstract
It has been widely recognized that topical treatment of mice with imiquimod (IMQ) cream results in generation of skin inflammation, which resembles human psoriasis. We previously reported that topical treatment with TLR7 agonists including IMQ and resiquimod also induced lupus-like systemic autoimmunity in wild-type mice. Thus, although IMQ treatment induces two distinct diseases, it remains unknown whether the underlying pathomechanism is common between them. In this study, we explored detailed kinetics of development of both diseases.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
