Abstract
A genetic tweak can make cells destroy themselves in the face of CRISPR gene editing, a trick with a variety of possible uses. CRISPR can be used to easily introduce changes to the DNA of living cells. It is a useful technique, but it would be handy to be able to make some cells CRISPR-resistant. For example, there is interest in storing information in DNA inside cells, and rendering some of them uneditable by CRISPR could enable us to make read-only reference copies. Here, La Page discusses a method developed by George Church at Harvard University to make human cells CRISPR-proof.
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