Abstract
Background and Aims : Fructose supplementation induces ketohexokinase (KHK), the first enzyme in its hepatic metabolism, promoting DNL and fatty liver. In the context of a study designed to examine the effects of bempedoic acid (BemA) on liver and plasma lipids in rats fed a high-fat diet supplemented with liquid fructose, we focused on the effects of BemA on KHK expression.
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