Abstract

Background: Present clinical study was conducted to evaluate the features of ketamine hydrochloride such as rapid induction, profound analgesia and minimal cardiovascular and respiratory depression with good airway maintenance. Aim: This study has been undertaken to prove the usefulness of ketamine in the present day anaesthetic practice as a sole anaesthetic agent for short surgical procedures and evaluate the features of ketamine hydrochloride such as: 1) Rapid induction; 2) Profound analgesia; 3) Minimal cardiovascular and respiratory depression with good airway maintenance. Methods: Study was conducted on 100 patients of either sex of different age group for various short surgical procedures. All patients were pre-medicated with Inj. Atropine 0.02mg/kg and Inj. Diazepam 0.2 mg/kg IV. Following this Inj. Ketamine 2mg/kg was given intravenously. During the course of anaesthesia patient was observed for the time of onset, duration of action, hemodynamic parameters, respiration, recovery from anaesthesia and certain side effects. Results: The onset of anaesthesia after intravenous injection of ketamine was within 20-54 sec [Mean 34.3+/- 8.7]. Ketamine as a sole anaesthetic agent in short surgical procedures-a clinical studyof effect of initial dose was between 9-20 min [Mean 16.9+/- 2.9].

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