Jérôme Waser

Abstract

Angewandte Chemie International EditionVolume 55, Issue 23 p. 6583-6583 Author ProfileFree Access Jérôme Waser First published: 22 January 2016 https://doi.org/10.1002/anie.201600180AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract “My biggest motivation is to see young students become independent researchers. My best investment was to wait one year for a good PhD student to join my group ...” This and more about Jérôme Waser can be found on page 6583. 1 Table 1. Jérôme Waser Date of birth: October 18, 1977 Position: Associate Professor, École Polytechnique Fédérale de Lausanne (EPFL) E-mail: jerome.waser@epfl.ch Homepage: http://lcso.epfl.ch/ Education: 2001 Diploma in Chemistry, ETH Zurich 2006 PhD with Prof. Erick M. Carreira, ETH Zurich 2006–2007 postdoc with Prof. Barry M. Trost, Stanford University Awards: 2009 Thieme Journal Award; 2011 A. F. Schläfli Award, Swiss Academy of Sciences; 2012 Silver Medal, European Young Chemist Award; 2013 ERC Starting Grant; 2014 Werner Prize, Swiss Chemical Society Current research interests: Development and application of synthetic methods, involving in particular electrophilic alkynylation, hypervalent iodine reagents and strained rings. Hobbies: Mountain running, badminton, reading My biggest motivation is to see young students become independent researchers. My best investment was to wait one year for a good PhD student to join my group. The downside of my job is to sound like a broken record (an expression of my postdoc advisor, Prof. Barry M. Trost, meaning always repeating the same things each time a new group member arrives). In retrospect I would never again believe that interpersonal relations are inconsequential for research. My favorite songs/pieces of music are the Valses by Chopin, Clair de Lune by Debussy, and Yesterday by the Beatles. My favorite quote is “Knowing is not enough; we must apply. Willing is not enough; we must do” (Johann Wolfgang von Goethe). What I look for first in a publication is the proposed reaction mechanism. My favorite place on earth is next to the Cabane du Grand Mountet in Val d'Anniviers (a mountain hut in the Swiss Alps surrounded by mountains and glaciers). My most exciting discovery to date has been the use of cyclic “hyperviolent” reagents for the umpolung of alkynes. My worst nightmare is that results from our research cannot be reproduced. The best advice I have ever been given is don't talk yourself out of an experiment (Erick M. Carreira). My 5 top papers: References 1“Direct Alkynylation of Indole and Pyrrole Heterocycles”: J. P. Brand, J. Charpentier, J. Waser, Angew. Chem. Int. Ed. 2009, 48, 9346; Wiley Online LibraryCASPubMedWeb of Science®Google ScholarAngew. Chem. 2009, 121, 9510. (Ethynylbenziodoxolone (EBX) reagents together with a gold catalyst for the alkynylation of heterocycles.) Wiley Online LibraryGoogle Scholar 2“Catalytic Selective Cyclizations of Aminocyclopropanes: Formal Synthesis of Aspidospermidine and Total Synthesis of Goniomitine”: F. De Simone, J. Gertsch, J. Waser, Angew. Chem. Int. Ed. 2010, 49, 5767; Wiley Online LibraryCASPubMedWeb of Science®Google ScholarAngew. Chem. 2010, 122, 5903. (Strained aminocyclopropanes are used in the synthesis of two different classes of alkaloids.) Wiley Online LibraryGoogle Scholar 3“Dynamic Kinetic Asymmetric [3+2] Annulation Reactions of Aminocyclopropanes”: F. de Nanteuil, E. Serrano, D. Perrotta, J. Waser, J. Am. Chem. Soc. 2014, 136, 6239. (Nitrogen-substituted strained rings can also be used in enantioselective intermolecular annulation reactions.) CrossrefCASPubMedWeb of Science®Google Scholar 4“Fast and Highly Chemoselective Alkynylation of Thiols with Hypervalent Iodine Reagents Enabled through a Low Energy Barrier Concerted Mechanism”: R. Frei, M. D. Wodrich, D. P. Hari, P. A. Borin, C. Chauvier, J. Waser, J. Am. Chem. Soc. 2014, 136, 16563. (A fascinating mechanism and high potential for applications in chemical biology.) CrossrefCASPubMedWeb of Science®Google Scholar 5“Platinum-Catalyzed Domino Reaction with Benziodoxole Reagents for Accessing Benzene-Alkynylated Indoles”: Y. Li, J. Waser, Angew. Chem. Int. Ed. 2015, 54, 5438; Wiley Online LibraryCASPubMedWeb of Science®Google ScholarAngew. Chem. 2015, 127, 5528. (An alternative synthetic method complementary to C−H alkynylation.) Wiley Online LibraryGoogle Scholar Volume55, Issue23June 1, 2016Pages 6583-6583 ReferencesRelatedInformation