Abstract

The value of drug resistant pattern and colicin type analysis as epidemiological markers of shigellasonnei has been questioned because of the pattern or type uniformity of recently isolated major strains.In this situation, Trehalose fermenting test was done on 1921 strains of Shigella sonnei collectedin this institute during the period from 1960 to 1972. They were mostly Trehalose fermentative and 83 strains of all have been found Trehalose non-fermentative.Through the facts that these Trehalose non-fermentative strains had been repeatedly isolated fromthe same patients or the carriers of the same outbreaks and this reaction is stable, it is believed that thisbiological property can be used as another tool for epidemiological marker of Shigella sonnei besidesdrug resistant pattern and colicin type.The drug resistant pattern and colicin type tested at the same time in this series showed these nonfermentativestrains have resistance to SM, CM, TC, SA, and NA (Nalidixic acid) and Type 14 colicintype.This is the first report on the isolation of Trehalose non-fermentative Shigella sonnei in Japan.

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