Abstract

A 40-year-old man developed encephalitis 3 days after onset of acute measles. He died 6 weeks later. Histopathological findings were consistent with late type of post-infectious measles encephalitis. Direct inoculation of a homogenate of fresh brain tissue obtained at necropsy into susceptible tissue cultures produced no infectious virus. However, co-cultivation of cells derived from this brain tissue with those of a continuous line of African green monkey kidney tissue culture yielded an infectious virus that was identified as measles.

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