Abstract

A new compound, designated rapiculine 1, was isolated along with fumigatin oxide 2 and spinulosin 3 from the culture filtrate of Ramichloridium apiculatum incubated in Czapek–Dox medium supplemented with 0.2% yeast extract, whereas only fumigatin oxide 2 was isolated from the culture filtrate of the same fungus cultivated in potato-dextrose medium. The structure of rapiculine 1 was elucidated by both spectroscopic means and its chemical reactions.

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