Abstract
1. 1. The isolation and characterization of a rapidly labelled RNA from mouse liver mitochondria is described. This RNA fraction was shown to have the characteristics of messenger RNA (mRNA). 2. 2. The rapidly labelled RNA fraction exhibits a molecular weight of 1.5 · 10 5 and is continuously synthesized both in vivo and in vitro for 120 min. 3. 3. The amino acid incorporation into mitochondria in vitro is slightly stimulated by this RNA fraction. It also prevents the inhibitory effects of chloramphenicol. 4. 4. Hybridization of the rapidly labelled RNA with mitochondria DNA suggests the mitochondrial origin of this RNA.
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