Abstract

Objectives: High levels of dopamine (DA) were described in human ovary (Lara et al., Endocrine, 2001) and DA receptors, namely D1 receptors in human granulosa cells (GCs; Mayerhofer et al., JCEM, 1999) and D1 and D2 receptors in horse follicles and Corpora lutea (King et al., Domest Anim Endocrinol, 2005) have hinted to a specific role of ovarian DA. Human GCs derived from women undergoing IVF are an adequate model for the follicle and the corpus luteum and were therefore employed in an attempt to decipher DA receptors and their functions.

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