Abstract
A preliminary animal study to investigate whether the incidence of scoliosis or the magnitude of curves can be changed by pharmacological sympathectomy in bipedal C57BL/6J mice model.
Highlights
The sympathetic nervous system (SNS), as an important part of autonomic nervous system, through its hypothalamic neuroendocrine control of puberty, menarche and skeletal growth may contribute significantly to the pathogenesis of adolescent idiopathic scoliosis (AIS)
Is sympathetic nervous system involved in the etiopathogenesis of idiopathic scoliosis? - A preliminary animal study in bipedal C57BL/6J mice model
Spine Surgery, the Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China
Summary
The sympathetic nervous system (SNS), as an important part of autonomic nervous system, through its hypothalamic neuroendocrine control of puberty, menarche and skeletal growth may contribute significantly to the pathogenesis of adolescent idiopathic scoliosis (AIS). Hyperactivity of the SNS has been reported to result in lower body mass index (BMI), lower bone mineral density (BMD), and longer extremities, which are commonly seen in AIS patients. The objective of this study was to investigate the effect of sympathectomy by way of pharmacological agents on the development of scoliosis in bipedal mice model
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
