Abstract
Mostly because the majority of patients with endometrial carcinoma present with early-stage disease, the anticipated survival rate is over 80% after primary surgery. Therefore, it would seem that this is one of the most straightforward cancers to diagnose and treat. Nevertheless, 6800 patients are expected to die from this disease in the United States in 2003, making endometrial cancer a source of intense clinical investigation in an attempt to identify patients at risk for relapse and death [ 1 Jemal A. Murray T. Samuels A. Ghafoor A. Ward E. Thun M.J. Cancer statistics, 2003. CA Cancer J Clin. 2003; 53: 5-26 Crossref PubMed Scopus (3360) Google Scholar , 2 Morrow C.P. Bundy B.N. Kurman R.J. Creasman W.T. Heller P. Homesley H.D. Graham J.E. Relationship between surgical–pathological risk factors and outcome in clinical stage I and II carcinoma of the endometrium a Gynecologic Oncology Group study. Gynecol Oncol. 1991; 40: 55-65 Abstract Full Text PDF PubMed Scopus (1252) Google Scholar , 3 Zaino R.J. Kurman R.J. Diana K.L. Morrow C.P. Pathological models to predict outcome for women with endometrial adenocarcinoma the importance of distintion between surgical and clinical stage. A Gynecologic Oncology Group study. Cancer. 1997; 77: 1115-1121 Crossref Scopus (181) Google Scholar ].
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