Abstract
Minimal pleural effusion (PE; defined as <10 mm thick) poses a diagnostic dilemma in non–small-cell lung cancer (NSCLC) staging. The 7th edition of the TNM staging system classifies malignant PEs as M1a metastasis. However, neither thoracentesis nor pleural biopsies are recommended for minimal PEs. Therefore, minimal PE is not accounted for in NSCLC staging. To address this issue, investigators retrospectively reviewed chest computed tomography scans of 2061 patients with NSCLC at a …
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