Abstract

With enhanced capillary electrophoresis (CE) injection the fold increase in peak heights relates to the fold increase in sensitivity. As a result, DNA profiles appear similar when the amount of DNA in the PCR was adjusted according to the sensitivity of the analysis. With enhanced CE injection, however, more drop-in alleles were observed. In (probabilistic) DNA profile interpretation, it seems opportune to account for an amount of drop-in that is in accordance with the sensitivity of the method.

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