Iodine Deficiency–Induced Goiter in Central New Jersey: A Case Series

Abstract

ABSTRACT Objective: We report 4 cases of iodine deficiency– induced goiter in minority women living in central New Jersey. Methods: Clinical presentations, laboratory data, thyroid 123I uptake, and thyroid sonograms were obtained from 4 minority women with iodine deficiency–induced goiter. The recent literature on the topic was also reviewed. Results: Four patients were diagnosed with iodine deficiency–induced goiter during a 4-year period in an endocrine clinic in central New Jersey. The diagnosis of iodine deficiency–induced goiter was made if the patient met the following criteria: (1) a diet history that indicated avoidance of iodized salt or seafood; (2) a 24-hour urinary iodine concentration of <100 μg; and (3) a decrease in the size of the goiter determined by ultrasonography of the thyroid after iodine replacement. Thyroid volume was calculated as width × length × height × π/6 cm3. Three of the four patients had an increase in radioactive iodine uptake. Conclusion: Iodine deficiency–induced goiter...