Abstract
Objective To explore the manifestation of pancreatic metastases （PM） using contrast- enhanced ultrasound （CEUS）. Methods Eleven patients with PM confirmed by pathology or CT/MR1 combined with clinical data were analyzed retrospectively.The manifestation on conventional ultrasound and the enhancement appearance on CEUS were analyzed.Results The primary malignant tumors included lung cancer （ n = 6）, breast cancer （ n = 1 ）, renal clear cell carcinoma （ n = 1 ）, gastric cancer （ n = 1 ）, rectal cancer （n = 1） and leiomyosarcoma of uterus （n = 1 ）. Eight patients had one lesion and three were multiple.The maximum lesion diameter was 2.0- 5.0 cm. Eight of the 11 patients showed hypoechoic on conventional US.Three patients were diagnosed as probably PM, one probably malignant and 7 undetermined by US.In the early stage of CEUS, two patients showed hyper-enhancement, six showed iso-enhancement and 3 showed hypo-enhancement.In the late stage of CEUS, nine patients （9/11） showed hypo-enhancement. Seven patients showed homogeneous enhancement.Six patients were diagnosed as PM, three malignant, one neuroendocrine tumor and one undetermined by CEUS.Conclusions PM showed certain characteristics on CEUS.The hyper- or iso-enhancement at the early stage of CEUS and history of primary cancer is helpful for diagnosis of PM. Key words: Ultrasonography; Microbubbles ; Pancreatic neoplasms ; Neoplasms metastasis
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