Abstract

The bactericidal effect of medicinal plants (Pyrus communis of Lystopadova variety, Arctostaphylos Adans, rhizomes of Potentills Erecta and Bischofite) on Staphylococcus aureus strain 209 and Escherichia coli strain 1257 was studied. According to the literature, it was found that the chemical composition of the studied plants contains flavonoids, phenolglycosides, tannins, triterpenoids, amino acids, essential oil, hydroxycinnamic acids, saponins, catechin, sanguinarin, which have antimicrobial effects. The objects of the study were 40 % tinctures of the leaves of Pyrus communis Noyabrskaya, Arctostaphylos Adans, and rhizomes of Potentilla erecta. The antimicrobial activity of plant-based herbal remedies was studied using the generally accepted method of “wells”. It was found that the tinctures in combination: 1) Arctostaphylos Adans with the addition of Potentills Erecta, Pyrus communis, Bischofite solution and 2) Arctostaphylos Adans + of Potentills Erecta + Bischofite have a more pronounced antimicrobial effect compared to other studied herbal remedies. The least pronounced effect of the tincture of pear leaf extract + bischofite was on Staphylococcus aureus strain 209 than on Escherichia coli strain 1257. The presence of the antimicrobial effect of tinctures from raw materials of Pyrus communis of the Noyabrskaya variety, Arctostaphylos Adans, galangal rhizome, and Bischofite indicates the expediency of further study of this composition. The presence of active substances with different pharmacological activity in plants contributes to the effective prevention of diseases of infectious etiology without side effects on the animal and human body. The raw materials of medicinal plants are less likely to contribute to various complications and, unlike traditional antibacterial drugs, in addition to antimicrobial action, have a mild positive effect on the macroorganism.

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