Abstract
Introduction: Exosomes, small microvesicles of endosomal origin, play a pivotal role in intercellular communication and various physiological and pathological processes. All cell types, especially cancer cells, release exosomes. These vesicles can induce tumor progression, metastasis, and drug resistance by altering the tumor microenvironment and transferring their content to target cells. Exosomes contain lipids, proteins, and genetic biomolecules such as DNA, mRNA, and miRNA with their contents varying depending on cell type and disease state. Despite their role in cancer progression, exosomes also show potential as therapeutic agents. They are effective carriers for targeted drug delivery due to their high biocompatibility and low immunogenicity. However, more extensive clinical trials are needed to evaluate the efficacy and safety of exosome-based therapies. Oncology researchers are encouraged to investigate exosome contents more precisely and design new therapeutic strategies utilizing these vesicles.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
More From: Journal of Shahid Sadoughi University of Medical Sciences
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.