Abstract

Abnormal angiogenesis is the underlying pathogenesis for blinding complications of retinopathy of prematurity. However, angiogenesis is physiologically necessary, hence VEGF variants have been implicated as either protective or associated with higher risk for ROP. This study aimed to search for SARDH gene variant association with angiogenesis in severe retinopathy of prematurity. SARDH has been implicated in some tumors.

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