Abstract
BackgroundInvasive urothelial carcinoma, lymphoma-like/plasmacytoid variant, is a rare histological type of bladder cancer similar to plasma cells and is an aggressive variant of urothelial carcinoma associated with a poor prognosis.Case presentationA 41-year-old Asian man was referred to our hospital due to macroscopic hematuria. Cystoscopy detected a non-papillary tumor, and a transurethral resection of the bladder tumor revealed pT1N0M0 bladder cancer. A pathological examination showed high-grade invasive urothelial carcinoma and a component of signet ring cell carcinoma. A follow-up of the transurethral resection with radical cystectomy was carried out, and a pathological examination showed infiltrating urothelial carcinoma, with partial features of the plasmacytoid variant. We added chemotherapy treatment with gemcitabine and cisplatin for two cycles. Our patient has been free from recurrence for 2 years.ConclusionsWe herein report the case of a patient with a plasmacytoid variant of urothelial carcinoma controlled with radial cystectomy and subsequent chemotherapy.
Highlights
Invasive urothelial carcinoma, lymphoma-like/plasmacytoid variant, is a rare histological type of bladder cancer similar to plasma cells and is an aggressive variant of urothelial carcinoma associated with a poor prognosis.Case presentation: A 41-year-old Asian man was referred to our hospital due to macroscopic hematuria
We report the case of a patient with a plasmacytoid variant of urothelial carcinoma controlled with radial cystectomy and subsequent chemotherapy
We report a case of a patient with plasmacytoid urothelial carcinoma that was successfully controlled with chemotherapy following radical cystectomy
Summary
Lymphoma-like/plasmacytoid variant, is a rare histological type of bladder cancer similar to plasma cells and is an aggressive variant of urothelial carcinoma associated with a poor prognosis.Case presentation: A 41-year-old Asian man was referred to our hospital due to macroscopic hematuria. Lymphoma-like/plasmacytoid variant, is a rare histological type of bladder cancer similar to plasma cells and is an aggressive variant of urothelial carcinoma associated with a poor prognosis. Lymphoma-like/plasmacytoid variant (PUC), is a rare histological type of bladder cancer similar to plasma cells and is an aggressive variant of urothelial carcinoma (UC) associated with a poor prognosis. We report a case of a patient with plasmacytoid urothelial carcinoma that was successfully controlled with chemotherapy following radical cystectomy. Case presentation A 41-year-old Asian man was referred to our hospital due to macroscopic hematuria. His past history included middle ear cholesteatoma and he had no smoking history. Cystoscopy detected a non-papillary tumor, and a transurethral resection of the bladder tumor (TUR-Bt) and a magnetic resonance imaging (MRI) scan revealed cT3N0M0 bladder cancer
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