Abstract
This is an introductory chapter it deals with the cytoskeleton. The cytoskeleton has many features, for example, the basic building blocks and transport functions of microtubules, myosin motor molecules, and actin microfilaments, which are conserved between cell types and even between organisms. Increasing knowledge of the properties of the cytoskeleton during normal cell function has been paralleled by an awareness that the cytoskeleton plays important roles in disease processes and cell pathology. It is now clear that abnormality in the cytoskeleton can have sufficient impact on cell physiology that altered cell function and diseases follow. The Cytoskeleton, A Multi-Volume Treatise the chapters deal with aspects of the cytoskeleton which reflect the specialized functions of the different cell types and also describe examples of changes in the cytoskeleton which occur during various pathological states. These studies bring the exciting area of cytoskeleton research into the domain of medical science.
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