Abstract
A 58-year-old hypertensive man with a perfused central retinal vein occlusion of 21 days' duration received 50 µg of intravitreal recombinant tissue plasminogen activator in 0.1 cc. Best-corrected visual acuity improved 2 weeks after the injection. Optical coherence tomography and fluorescein angiography demonstrated resolution of cystoid macular edema and improvement of venous outflow. Intravitreal tissue plasminogen activator may be a useful treatment for central retinal vein occlusion with a duration of 21 days or less. [Ophthalmic Surg Lasers Imaging 2003; 34:350–352.]
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