Intravascular Ultrasound Analysis of Coronary Stent Implantation with High Pressure Balloon Inflation

Abstract

Background：The intracoronary stent implantation is regarded as an effective treatment modality to reduce restenosis. However, subacute stent thrombosis and subsequent anticoagula-tion therapy have been major problems after stenting. The high-pressure inflation stenting reduced the incidence of stent thrombosis and resulted in less need of anticoagulation therapy. We intended to analyze the high-pressure inflation stenting with intravascular ultrasound(IVUS and to evaluate different IVUS criteria of optimal stenting. Method：One hundred and forty eight patients with 160 lesions were treated with 175 stents of various types. IVUS images were obtained after angiographic optimization(<10% of residual stenosis with high-pressure inflation stenting. The quantitative and qualitative off-line measurements of IVUS parameters were performed. Results：More high-pressure or larger-sized balloon inflation was needed in 32 lesions(20% after IVUS. The incomplete stent apposition was observed in 5 lesions(3%. The edge dissection occurred distally or proximally to stented site in 19 lesions(12%. The plaque prolapse was observed within the stent in 24 lesions(15%. In single stent implantation for discrete lesions, optimal stent expansion defined by IVUS was achieved in 69% with minimal stent lumen area of 90% of distal reference lumen area and in 75% with minimal stent lumen area of 80% of average reference lumen area. The IVUS criteria of minimal stent lumen area 9mm