Abstract
(Anesth Analg. 2016;123:690–697) The gold standard for pain control is intrathecal (IT) morphine, with an optimal dose for postcesarean analgesia ranging from 0 to 500 μg. However, there have been national shortages of preservative-free morphine, and dose-dependent opioid-induced side effects (nausea, pruritus, sedation, and respiratory depression) do occur. IT hydromorphone is a potential alternative for providing postcesarean analgesia. The authors of the present study thus identified dosages of IT hydromorphone that provided effective analgesia in 90% (ED90) of patients.
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