Abstract
Simultaneous computer recording of the parameters of external respiration, systemic and cerebral blood circulation, arterial pressure, oxygen saturation of hemoglobin, and tissue oxygen tension has been used to study the intrasystemic and intersystemic rearrangements at different stages of acute hypoxia caused by breathing hypoxic oxygen–nitrogen mixtures containing 6.8–8.0% oxygen. It has been found that all main vital systems of the body are involved in the response to hypoxia; however, the degree of their involvement and the changes in individual parameters vary considerably in different subjects. The functional strain of some systems may remain almost constant throughout the period of hypoxia, whereas the strain of others may gradually increase or decrease. It has been found that each stage of hypoxia is characterized by certain limits of the strain (involvement) of the functional reserves of oxygen supply systems; if the functional strain goes beyond these limits, then either intrasystemic and intersystemic relationships are disorganized or compensation reserves are overspent and the time of tolerance to hypoxia is decreased.
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