Abstract

An 83-year-old Caucasian patient was referred with bilateral vitritis treated with topicalcorticosteroids for 6 months. The patient had had a history of right testicular B-cell lymphoma10 years ago, which was treated with an orchidectomy followed by six rounds of CHOP-typechemotherapy.Ophthalmologic examination revealed a best corrected visual acuity of 50/100 in the right eye(RE) and 30/100 in the left eye (LE). Anterior segment examination was normal. Intra-ocularpressure was 15 mmHg in both eyes.Fundus examination disclosed mild vitritis and multiple pin-like creamy lesions in the deepretina of both eyes. A fluorescein angiography disclosed multiple pinpointed hyperfluorescentlesions (Fig. 1).An anterior chamber aspiration revealed an inter-leukin-10 (IL-10) of 314 pg/ml (normal <8pg/ml) and 150 pg/ml in the aqueous of the LE and RE, respectively.A diagnostic vitrectomy of the LE confirmed the presence of atypical lymphoid B-cells withan

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