Abstract
It is an established fact that intralesional injections of triamcinolone will result in temporary involution of most psoriatic lesions.1,2The purpose of this report is to note the effects produced by injecting different doses of triamcinolone acetonide into various parts of the same lesion. Large lesions were chosen to permit such injections and to allow untreated parts of the same lesion to be used as the control. The doses,*suspended in 1 cc. volume and diluted with saline when necessary, varied from 10 mg. to 0.07 mg. Photographs were taken approximately once weekly. No local treatment was permitted throughout the course of the experiment, and all patients were hospitalized. In most instances the area of clearing was roughly proportional to the concentration of triamcinolone acetonide injected into different parts of a lesion (Figs. 1 and 2b).† The factor which limited the upper dose was the appearance
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