Abstract
A 75-year-old female incidentally presented with an enhancing intraluminal gallbladder mass, main bile duct dilatation and anomalous pancreaticobiliary junction (APBJ) during the staging of gastric adenocarcinoma. Histopathological analysis confirmed the diagnosis of intracholecystic papillary-tubular neoplasm. Intracholecystic papillary-tubular neoplasms (ICPN) of the gallbladder are rare gallbladder neoplasms, defined as intramucosal, preinvasive, exophytic, mass forming lesions. An association between choledochal cysts and anomalous pancreaticobiliary junction with gallbladder neoplasms is well known, and this case potentially illustrates gallbladder carcinogenesis related to these biliary anomalies.
Highlights
Case presentation A 75-year-old female presented with occasional epigastric pain, lasting for more than 1 year
Pathological findings Histopathological analysis confirmed the diagnosis of intracholecystic papillary-tubular neoplasm, of foveolar gastric-type, with low-grade and high-grade dysplasia and a small invasive adenocarcinoma component (Figures 8 and 9), which accounted for less than 5% of the tumour volume
A 75-year-old female incidentally presented with a gallbladder lesion, main bile duct dilatation and anomalous pancreaticobiliary junction (APBJ) during the staging of gastric adenocarcinoma
Summary
Case presentation A 75-year-old female presented with occasional epigastric pain, lasting for more than 1 year. Diffuse dilatation of the main bile duct was present, with no identifiable obstructive lesion (Figure 2).
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