Abstract

SUMMARYBy means of double‐barrelled microelectrodes filled with appropriate salt solutions we have observed the effects of injecting, iontophoretically, sodium, potassium and chloride ions into muscle fibres of the rabbit right ventricle.Injection of sodium ions produced a reversible decline in maximum rate of depolarisation and amplitude of the action potential with no change in shape or voltage‐time course of the action potential.Injection at equivalent rates of equivalent amounts of potassium or chloride ions had no effect.The changes observed after sodium injection are in agreement with the prediction of the mathematical model of the cardiac action potential described by George and Johnson (1962).

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.