Abstract
The main objective of the study is to assess the efficacy of intra-articular (IA) injections of hyaluronic acid (HA), compared to corticoids in patients with osteoarthritis of knee in both the long-term follow-up, and whether there is a difference. Randomized study, from Mars 2015 until June 2016, compared two groups of patients with knee osteoarthritis; 1st group: injected by corticoids (only 1 injection/knee/month, n = 14), controlled by group (3 injections/knee of HA, n = 18). Evaluated by: pain intensity; Visual Analog Scale (VAS), Lequesne Algofunctional Index, and quality of life. The follow-up time was 12 months. After 12 months of follow-up, both treatment groups showed improvement in knee function, the corticoids group showing a greater improvement compared to HA group; in pain relief, in overall Lequesne Algofunctional Index, and quality of life. The IA injection of corticoids was better to improve the symptomatology in the long-term, corticods provided pain relief and quality of life in patients with knee OA, compared with IA of hyaluronic acid. However, IA hyaluronic acid is a good alternative the delay the surgery.
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