Abstract
A SPECIFIC duodenal calcium binding protein (CaBP) has been implicated in calcium absorption in many animal species1 and adaptation of duodenal adsorption to increased calcium intake is accompanied by its increase. Vitamin D deficiency depletes and repletion restores CaBP with corresponding changes in duodenal absorption. The exact role of CaBP in calcium absorption has, however, not yet been defined. We studied calcium absorption in the diabetic rat, in which model system previous studies have shown enhanced carbohydrate and amino acid absorption2,3, and found decreased duodenal but normal ileal absorption4. Since CaBP may be important in duodenal calcium absorption, we report here studies of CaBP in rats made diabetic with alloxan.
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