Abstract
Aim: To analyze the relationship between daily blood pressure biorhythms and left ventricular myocardial hypertrophy in working-age men with arterial hypertension. Materials and Methods: Fifty-seven men with AH (mean age: 44.6±1.3 years) underwent Echo-CG and daily ABPM. Non-dipper and night-peaker patterns indicated BP biorhythm disturbances, while normal dipper and over-dipper patterns indicated undisturbed BP biorhythms. LVH was defined as LMMI > 115 g/m^2. Results: About 60% of participants exhibited diurnal BP rhythm disorders, with a higher prevalence of LVH in this group compared to those with normal BP biorhythms (32% vs. 22%, p>0,05). Patients with normal daily BP biorhythms had significantly higher circadian indices of HR, systolic and diastolic BP, and double product compared to those with disturbed BP rhythms. Conclusions: In young men with "non-dipper" and "night-peaker" patterns, LVH appears to be more pronounced than in those with normal daily BP biorhythms. This approach may optimize the timing of antihypertensive drug administration.
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