Abstract
Interproximal in situ Plaque pH after a Sugar Challenge in Relation to Caries in Adults before and after Short-Term Use of 1.5% Arginine Toothpaste
Highlights
The evidence of the anti-caries effect of arginine toothpaste has been questioned and randomised trials independent of commercial interests have been required
Compared with before the test period of using arginine toothpaste, the sugar challenge resulted in statistically significant higher pH values after arginine use in the caries group only (Table 1)
The baseline pH before the challenge was in this group significantly increased at the molar sites 25/26 and 46/45 after using arginine toothpaste (Table 1)
Summary
The evidence of the anti-caries effect of arginine toothpaste has been questioned and randomised trials independent of commercial interests have been required. Despite a global decline in dental caries the end of the last century it still remains a significant public health concern [1]. Dental caries is considered a multifactorial disease with a complex aetiology [2]. A low pH biofilm environment is related to the activity of acidogenic/aciduric microorganisms’, which can lead to development of a caries lesion. The alkalinogenic potential of the dental biofilm can, counteract acid production and the demineralization process, and thereby control and prevent dental caries [4]. Clinical studies have revealed a positive correlation between alkali production and caries resistance in different age groups [5,6]
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