Abstract
Background: Several studies demonstrate the existence of cytokine dysregulation in patients with acute myeloid leukemia (AML), which may be associated with pathogenesis, disease progression, and patient survival. The aim of this study was to evaluate the association of IL-6 levels and the risk of AML among Iraqi patients. Methods: A case-control study was carried out to analyze IL-6 levels in the serum of 60 patients with AML and a healthy control group. In this study, AML patients were divided into two groups: 30 AML before receiving treatment and 30 AML after receiving treatment. A variety of biochemical and anthropometric measurements, such as sex and age, BMI, serum IL-6, ALT, AST, urea, and creatinine levels, were examined in this study. Results: With regard to the patient group, the BMI, RBC, WBC, Hb, Lymphocytes, neutrophils, platelets, serum ALT, AST, urea, and creatinine levels revealed a significant difference compared with the control group.
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