Abstract

The resting potential of the scala media (EP) in the first turn of the guinea pig's cochlea was altered by the application of currents. The EP as well as the cochlear microphonics (CM) and the summating potential (SP) were enhanced when the source electrode was in scala media, whether the sink electrode was in the scala tympany or scala vestibuli. Using the scala media electrode as the sink for the current, caused decreases in these potentials. A linear relationship exists between the changes in the cochlear responses, CM, and SP (in decibels), and the changes in the EP. The SP increased or decreased by 1 dB for a 10% variation in the EP value. The corresponding change in the CM was one-third of the change in the SP. [This work was supported by the National Institute of Neurological Diseases and Blindness Research Grant.]

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