Abstract
The uptake of tritiated steroid hormones and their passage through the dense layer of the plasma membranes of rat hepatocytes and rabbit ghost erythrocytes was investigated. The degree of uptake of steroid hormones by the plasma membranes diminishes in the following order: progesterone > testosterone > estrone > prednisolone > estriol. The degree of uptake of the hormones correlates with their solubility in lipids and with the resulting release of enzymes from the lysosomes. Meanwhile it shows negative correlation with the rate of passage through the dense layer of the membranes. The character of uptake of steroid hormones is independent of the role of the plasma membranes.
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