Abstract
Many observations concerning intelligence could be explained if much variance in intelligence reflects myelination differences. More intelligent brains show faster nerve conduction, less glucose utilization in positron emission tomography, faster reaction times, faster inspection times, faster speeds in general, greater circumference and volume, smaller standard deviation in reaction times, greater variability in EEG measures, shorter white matter T 2 relaxation times, and higher gray-white matter contrast with magnetic resonance imaging. Also explainable are peculiarities of the increased reaction times and standard deviations with number of choices and complexity, reaction time skewness, the shorter latencies in evoked potentials, shorter latencies to the P300 wave, the high glial to neuron ratio in Einstein's brain, less glucose utilization per unit volume in large brains, certain results related to lipids, essential fatty acids, and cholesterol in adults and premature babies, and the survival of genes for lower intelligence. Children's improved performance with maturation might result from myelination. The slowing of response times with age, the decline in intelligence, and increased T 1 relaxation times could be explained. Differential myelination in the mouse brain might be able to explain the heterosis observed for myelination, brain size, caudal nerve conduction velocity, and maze performance observed.
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