Abstract
BACKGROUND: Integral parameters, in particular, the oxidative stress coefficient are informative and can be used both for evaluation of pathological conditions and compensatory-adaptive reactions of the organism.
 AIM: To investigate an integral coefficient the activity of nonspecific reactions of lipid peroxidation in adolescent girls of the Buryat, Evenki and Tofalar ethnic groups, as compared to the non-indigenous ethnic groups, by applying.
 METHODS: Total 190 adolescent girls (Buryats, Evenki and Tofalar, and nonindigenous population (for example of Russians)) living in the Irkutsk region were the objects of research. The survey was carried out in expeditionary conditions, in the territories of compact residence of ethnic groups. To calculate the integral coefficient (oxidative stress coefficient), spectrophotometry and fluorometry methods we implemented. The individual indicators: primary, secondary, and final products of lipid peroxidation as well as antioxidant defense components were measured.
 RESULTS: According to the obtained data, a lower content of diene conjugates (DC) (p 0.0001), ketodienes and conjugated trienes (KD and СT) (p=0.0003), -tocopherol (p 0.0001) with elevated levels of TBA-active products (p=0.0074) and superoxide dismutase activity (p=0.0008) in the Buryat ethnic girls group relative to similar parameters of girls in the non-ingenious population was observed. Girls of Tofalar ethnic group had higher values of DC (p=0.0009), with reduced values of KD and CT (p=0.0044) compared to the non-indigenous population. There were no differences among girls of the Evenk ethnic group relative to Russians. An integrative analysis of the state of nonspecific lipid peroxidation reactions using the coefficient showed no significant differences between the studied groups.
 CONCLUSION: The conducted study demonstrates certain changes in the lipid peroxidationantioxidant defence system, in the absence of changes in the total indicator among girls representing Siberian ethnic groups and the Russian population living next to them, which can be the basis for subsequent monitoring of their health status.
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