Abstract
The diffusive permeability of insulin in polyhydroxyethyl methacrylate (37.1% water), polyhydroxyethyl acrylate (51.8% water), polymethacrylic acid (67.5% water), and cuprophane PT-150 membranes was determined and correlated with the weieht fraction of water in the membrane. Insulin diffusivity in the membranes was determined to be 1.0×10−6cm2/sec, which is in reasonable agreement with literature values for insulin diffusivity in water.
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