Abstract
Background: The third international consensus definition for sepsis and septic shock operationally defines septic shock as the requirement for vasopressor support to maintain a mean arterial pressure ≥65mmHg, with a serum lactate of >2.0 mmol/L after adequate fluid resuscitation. The rationale for including serum lactate in the definition was to improve the ability of the definition to discriminate between patients at higher and lower risk of death. The utility and feasibility of this definition has been questioned, especially in the resource-limited environment.
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