Innovations in photocatalytic trifluoromethylation: Role of heterogeneous Bi4NbO8Cl in radical generation

Abstract

Photocatalytic selective trifluoromethylation reactions have garnered significant attention, particularly for their applications in pharmaceuticals, agrochemicals, and materials science. However, existing heterogeneous catalysts such as graphitic carbon nitride, CdS nanorods, and Au@ZnO core–shell nanoparticles exhibit certain limitations, including low catalytic efficiency, inadequate selectivity, and demanding reaction conditions. To address these challenges, we have developed a novel heterogeneous photocatalyst, i.e., Bi4NbO8Cl, and systematically investigated its performance in visible-light-induced hydroxytrifluoromethylation of alkenes and trifluoromethylation of (hetero)aromatics. Notably, the Bi4NbO8Cl photocatalyst exhibits remarkable stability and reusability, maintaining its performance and structural integrity over five cycles. These findings highlight the economic and practical potential of Bi4NbO8Cl, positioning it as a promising candidate for industrial applications in photocatalysis.