Abstract

IntroductionThe introduction of high-dose and liquid toxins has revolutionized aesthetic medicine, offering patients enhanced options for treating glabellar lines with improved convenience and efficacy. PurposeThis study aims to analyze and discuss recent trials of high-dose and liquid toxins for treating moderate to severe glabellar lines, underscoring their significance in advancing aesthetic medicine. MethodsA comprehensive review of clinical studies and patient outcomes data was conducted to assess the effectiveness and safety profiles of high-dose and liquid toxins, including OnabotulinumtoxinA, AbobotulinumtoxinA, IncobotulinumtoxinA, DaxibotulinumtoxinA, PrabotulinumtoxinA NivobotulinumtoxinA, and RelabotulinumtoxinA. ResultsClinical studies have demonstrated that high-dose toxins provide prolonged muscle relaxation and reduced wrinkles, with well-tolerated safety profiles. Liquid toxins offer comparable efficacy to traditional formulations with quicker onset and extended duration of effects, contributing to high levels of patient satisfaction. ConclusionThe introduction of high-dose and liquid toxins represents a significant advancement in aesthetic medicine, providing patients with more options for achieving natural-looking, long-lasting results in the treatment of glabellar lines. Further research and optimization efforts are needed to maximize the benefits of these treatments and address the remaining challenges.

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