Abstract
The inhibitory effects of high density lipoprotein (HDL) subfractions on the in vitro complex formation between plasma low density lipoprotein (LDL) and arterial elastin were studied. 1. (1) The inhibitory effects were significantly higher with HDL 3 than HDL 2, and with HDL-without E than HDL-with E. 2. (2) The inhibitory effect of a phospholipid complex with apoHDL 3 was higher than that with apoHDL 2. 3. (3) In contrast with the inhibitory effects, the binding abilities of HDL 2 and HDL-with E to elastin were significantly higher than those of HDL 3 and HDL-without E. 4. (4) These results suggest that the inhibitory effects of HDL subfractions are not due to competitive binding with arterial elastin.
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