Abstract
OXIDATIVE STRESS AND LEUKOCYTE APOPTOSIS IN DAIRY COWS NATURALLY INFECTED WITH BOVINE LEUKEMIA VIRUS This study investigates the interrelation between oxidative stress and immune system alterations, especially apoptotic processes. A total of 15 dairy cows were divided according to their hematological profiles and results from serological examination. Blood samples were collected for detection of bovine leukemia virus. Methods included agar gel immunodiffusion (AGID), enzyme-linked immunosorbent assay (ELISA), hematological, mononuclear and cell death analysis, and determination of reduced glutathione (GSH), glutathione peroxidase (GSH-Px), and malondialdehyde levels. Research findings revealed high survival rates of Bcells and the involvement of oxidative stress leading to disease progression and lymphocyte resistance.
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