Abstract
Miniaturized and integrated analytical devices, including chemical sensors, are at the forefront of modern analytical chemistry. The construction of novel analytical tools takes advantage of contemporary micro- and nanotechnologies, as well as materials science and technology. The goal of this study was investigate electron transfer resistance in model solution and protein adsorption using integrated electrochemical cell with different geometry.
Highlights
Electrochemical impedance spectroscopy (EIS) is one of the techniques used in the measurement of biological and biochemical layers, e.g., bacteria and proteins
Even Integrated electrochemical cells (IEC) with small WE surface can be used in further measurements
Miniature integrated impedance sensors fabricated in Low Temperature Cofired Ceramic (LTCC) technology were used in measurement with model solution containing iron ions and for investigate protein adsorption on WE
Summary
Electrochemical impedance spectroscopy (EIS) is one of the techniques used in the measurement of biological and biochemical layers, e.g., bacteria and proteins. EIS is a technique, which monitors the electrical response of the system studied after application of a periodic small amplitude alternating current (AC) signal. Cyclic voltammetry (CV) is proven to be very effective for the study the redox process on gold electrode [1], characterization of biomolecule-modified electrode surfaces and the analysis of the alteration in the interfacial properties originating from biomolecular recognition events. Such measurements are performed in the electrochemical cells which consists of individual electrodes placed inside the macroscopic vessel. Integration of the electrochemical cell electrodes on the surface of the substrate allows for their miniaturization and facilitates the increase of the number of simultaneously conducted experiments in multiplexed measurement system
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