Abstract

In frog atrial bundles it is possible under voltage clamp conditions to distinguish between a “phasic” component of mechanical response, depending on Ca++ influx, and a “slow” component, which does not directly depend on the presence of extracellular Ca++ (Vassort et Rougier, 1972). The present results suggest that the “slow” component can be abolished by substituting LiCl for NaCl. The hypothesis is advanced that a displacement of Ca++ by Na+ from some intracellular binding sites by a variation of membrane potential or [Na]i causes the “slow” phase of contraction.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.