Abstract
One of the most pressing problems of modern science is the systematic study of natural processes, forecasting and complex assessment of changes in the environment under the influence of anthropogenic load. Blood composition is a relatively constant indicator, which is at the same time one of the labile systems of laying hens. Physiological processes that occur in the body, largely affect the quality of blood. Hematological studies make it possible to study in more detail the effect of cadmium on the body of chickens, on the basis of which a more specific development of the scheme of treatment and prevention of cadmium toxicosis in poultry is possible. The aim of this study was to investigate the effect of milk thistle, methifene and silymevitis on the morphological indices of laying hens in the development of chronic cadmium toxicosis. 32 laying hens, 78 weeks of age, were selected for the study. Four experimental groups were formed: control and three experimental. The control group (C) chickens and the three experimental groups were cadmium sulfate 4 mg/kg body weight in water. The chickens of the experimental group E1 with feed were fed the fruits of milk thistle spotted at a dose of 2.0 g/kg of feed once a day for 30 days. The chickens of the E2 experimental group were fed methifene at a dose of 0.28 g/kg of feed once a day for 30 days with feed. The chickens of the E3 experimental group were fed a sylimevit at a dose of 0.36 g/kg of feed once a day for 30 days. Drinking cadmium sulphate to laying hens at a dose of 4 mg/kg body weight contributed to a decrease in red blood cell count, hemoglobin level and an increase in leukocyte counts. With cadmium load of laying hens, milk thistle, methifene and sylimevit have a positive effect on the morphological parameters of the blood. In chronic cadmium toxicosis in laying hens, the best normalizing effect on the morphological parameters of the blood of experimental chickens is sylimevit, compared with methifene and milk thistle.
Highlights
The problem of environmental pollution by Cadmium, which is one of the consequences of the intensification of industrial and agricultural production, has become relevant today (Uetani et al, 2005; Nazaruk et al, 2015; Sachko et al, 2016)
Hematological studies make it possible to study in more detail the effect of cadmium on the body of chickens, on the basis of which a more specific development of the scheme of treatment and prevention of cadmium toxicosis in poultry is possible
When setting milk thistle to chickens in the experimental group E1, we found an increase in the number of red blood cells in their blood for the 14th day of the experiment by 5 % relative to the values of the control group of chickens who were not treated
Summary
The problem of environmental pollution by Cadmium, which is one of the consequences of the intensification of industrial and agricultural production, has become relevant today (Uetani et al, 2005; Nazaruk et al, 2015; Sachko et al, 2016). Cadmium and its compounds are immunotoxicants that cause impaired functioning of the body's immune system, reduce resistance to infections, contribute to the formation of allergic, autoimmune and cancer pathologies (Ali et al, 1986; Salvatori et al, 2004; El-Refaiy & Eissa, 2012; Peng et al, 2015; Gutyj, 2015). In this regard, the particular effects of Cadmium on human and animal organisms have been the subject of detailed study, especially over the last decade
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